Pascale Gaujacq

Paris, France

1959 / Class of '06 / Bone lesions: skull, arm, fracture repaired / Type: IgA Lambda / VAD, Thal/Dex, Velcade, CHOP 14 / Updated: 3/07

(By her sister, Catherine: edfinacg@aol.com or isisixia@aol.com)

Pascale (left) and me (right)

	Born December 1959
	Diagnosed March 2006 by Professeur Varet Paris - Hopital Necker
	Bone lesions at diagnosis (skull, arm long bone, costal fracture repaired)
	IgA Lambda, normal LDH, stage III at diagnosis
	Major treatments: VAD (3 cycles), Thal/Dex (3 months), Velcade (5 cycles), CHOP 14 (1st cycle)
	Collection of stem cells in July 06
	Pic Beta=16, High Beta-2 microglobulin since 12/06 (Velcade), LDH=1600 since 12/06 (Velcade).

Pascale is in good health (!) and no one could tell she is sick. She is a great person, with a wonderful spirit! We grew up in France in a rural area. Pascale lives in Paris since 1982 and has been a high level consultant in the telecommunications industry for twenty years. She was an airplane stewardess for 3 years in her 20's.

Pascale responded well to each first 2 cycles of every new induction treatment, and then each time the beta peak plateaued. It is just as if the 15 value was a minimum that would trigger an aggression of the disease. The first time she reached 15 after Thal/Dex and was awaiting transplant, the peak took off to 50. The second time she reached 15 with Velcade, LDH and Beta-2-microblobulin took off. Her Beta peak is stable to date around 15, but she has 70% dystrophic plasma cells in her bone marrow. The doctors cannot proceed with autologous transplant until LDH is back to normal, and she is now undergoing 3 cycles of CHOP 14, usually used with Lymphoma.